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Since
dangerous game is normally taken up close, the superior practical
range of the 06 may not be significant here, but it is a
general-purpose cartridge, whereas today the 45-70 is a specialist
tool. In Jim West's "Co-pilot" the 45-70 is a jewel for the big
game guide, but there are not many of those. In any case, if you
put the bullet in the right place, either round will do the
job.