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ORAL: Use as first Opioid Analgesic: -Initial dose: 10 to 20 mg orally every 4 to 6 hours as needed for pain Maximum initial dose: 20 mg Conversion from Other Oral Opioids to Oral Oxymorphone: -Determine equipotent dose using published potency tables; it is safest to start therapy by administering one-half the calculated total daily oxymorphone requirement in 4 to 6 equally divided oral doses every 4 to 6 hours and gradually adjust the dose as needed.
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